Evidence library
What does the evidence actually say?
Straight answers to the real questions about GLP-1s, each graded two ways: how strong the evidence is, and whether it comes from people actually taking these drugs. No hype, every claim sourced.
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Muscle & lean mass
Will I lose muscle on a GLP-1?
How much muscle comes off with the fat, whether it matters, and what holds onto it.
5 claims
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Bone density
Do GLP-1s weaken your bones?
Weight loss can pull bone density down. What that means, and what protects it.
4 claims
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Exercise & training
Do you need to exercise on a GLP-1?
Why strength training is the one habit that protects both muscle and bone.
4 claims
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Protein
How much protein do you need on a GLP-1?
How much, measured against which body weight, and where the advice is sponsored.
5 claims
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Nutrients & supplements
Do GLP-1s leave you short on nutrients?
The deficiency data is real. The supplement fixes being sold are mostly sponsored.
6 claims
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Stopping & weight regain
What happens when you stop a GLP-1?
Most of the weight comes back. What that means, and what actually holds it off.
6 claims
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How well they work
How much weight do GLP-1s actually take off?
The headline numbers, who they apply to, and the support that came with them.
6 claims
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Side effects & safety
What are the side effects of GLP-1s?
Which are common and manageable, which are rare, and which are still unproven.
5 claims
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The care gap
Is the drug enough on its own?
The support the trials included, that most prescriptions leave out.
6 claims